A miscarriage is a tragic event for couples who want to have a child together. The first question a woman usually asks herself is: “Did I do something wrong?”
The truth is: a woman cannot cause a miscarriage through her behavior, such as stress, work, sex, or light athletic activity.
Recurrent miscarriage ias medically defined as a series of three pregnancies that end in miscarriage. This is also called “habitual abortion” or recurrent pregnancy loss (RPL).
The causes for this are complex. They also require a specialized diagnostic approach:
- Exclusion of immunological factors:
A woman’s immune system plays a role in accepting the embryo into the womb and into the mother’s immune system. An imbalance between the mother’s immune defenses or, for instance, an increased percentage of natural killer cells in the blood or endometrium can cause a rejection of the pregnancy.
- Organic clarification:
Exclusion of abnormalities of the womb (uterus subseptus, cervical incompetency, polyps, etc.)
- Genetic clarification:
Creation of a chromosomal analysis for the man and woman to exclude congenital (genetic) disorders
- Exclusion of malfunctions in the coagulation system:
An increased tendency towards blood clotting may lead to small thrombosis (blood clots) which can cause vascular occlusions in the endometrium, causing the pregnancy to fail due to lack of blood supply
- Exclusion of chronic inflammation:
A chronic infection which is not perceived subjectively can also cause a pregnancy to miscarry
- Exclusion of a male cause for repeated miscarriages:
The embryo is only as good as the egg and sperm cells from which it is created. A sperm analysis under high-resolution microscope (MSOME spermiogram) is recommended, as well as monitoring the semen analysis for an elevated number of broken strands in the DNA (HALO sperm)
- Exclusion of hormonal causes:
A lack of progesterone, as well as other hormonal causes such as thyroid dysfunction can significantly increase the risk of a miscarriage.